Air pollution linked to breast cancer, says study.
Air Pollution Linked to Higher Rates of Breast Cancer
A groundbreaking study conducted by a cross-collaborative team of scientists at the National Institutes of Health (NIH) reveals a concerning connection between air pollution and breast cancer.
Researchers at the National Institute of Environmental Health Sciences (NIEHS) and National Cancer Institute (NCI) discovered that individuals residing in areas with high levels of air pollution, specifically measured as particulate matter (PM2.5), have an overall 8 percent higher incidence of breast cancer compared to those living in areas with lower levels.
Furthermore, the study found a correlation between PM2.5 concentration and tumor type. The research, primarily focused on postmenopausal women, demonstrated that women living in regions with high PM2.5 levels had a 10 percent greater incidence of estrogen receptor-positive (ER+) tumors, the most common type of breast cancer. However, no link was found between highly concentrated PM2.5 regions and estrogen receptor-negative (ER-) tumors, as reported in the Journal of the National Cancer Institute.
These findings provide further evidence of a connection between breast cancer and endocrine disruption. Compounds like metals and phthalates, known endocrine disrupters, attach to PM2.5 particles, reinforcing the link.
Interestingly, breast cancer rates varied depending on the region. The study assessed eight locations, including six states (California, Florida, Pennsylvania, New Jersey, North Carolina, and Louisiana) and two metropolitan areas (Atlanta and Detroit). Women living in catchment areas with high levels of PM2.5, such as Atlanta and North Carolina, experienced more pronounced breast cancer rates. Additionally, the study observed the greatest increases in breast cancer incidence among women who had higher PM2.5 levels near their homes prior to enrolling in the study.
“Although this increase is relatively modest, these findings are significant given that air pollution is a ubiquitous exposure that impacts almost everyone,” said Alexander White, lead study author and head of the Environment and Cancer Epidemiology Group at NIEHS. “These findings add to a growing body of literature suggesting that air pollution is related to breast cancer.”
Hundreds of Different Chemicals
According to the U.S. Environmental Protection Agency (EPA), particulate matter, also known as particulate pollution, refers to a mixture of tiny solid particles and liquid droplets containing hundreds of different chemicals found in the air. These particles can be in the form of dust, dirt, soot, or smoke.
Exposure to PM2.5 typically occurs near construction sites, unpaved roads, fields, smokestacks, or fires. Particulate matter can also be emitted as a result of complex reactions between chemicals from power plants, industries, and motor vehicle exhaust and combustion.
PM2.5 particles pose the greatest health risk as they are small enough to be deeply inhaled and can potentially enter a person’s bloodstream.
Historic
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